A General Review of the antibiotics Mupirocin and Cefuroxime on Paronychia caused by S. Aureus and S. Pyogenes species

Abstract

This article will focus on the treatment of paronychia with cefuroxime and mupirocin, which are two different types of antibiotics frequently prescribed by medical professionals for the treatment of nail infections caused by common pathogenic bacterial species. Cefuroxime is an antibiotic isolated from a fungus and is characterized as a type of class II cephalosporin that belongs to the class of B-lactam antibiotics that binds to penicillin-binding-proteins in bacteria, therefore inhibiting bacterial peptidoglycan (cell wall) synthesis and kills the cell. Mupirocin (more commonly known as Bactroban) is another antibiotic that is isolated from a fellow bacteria species and works by obstructing bacterial aminoacyl-tRNA synthesis in various species of bacteria that may be susceptible to the mechanism. However, the application of these antibiotics onto infected regions does not guarantee a complete elimination of the pathogens due to the rise of antibiotic resistance genes throughout the bacterial population. A short discussion will follow all the presented materials, as well as the referenced materials.