Treating Psoriasis: Simple Introduction about Acitretin and Tacrolimus

Authors

  • Aofei Yang

DOI:

https://doi.org/10.61173/2ypce089

Keywords:

- psoriasis, keratinocytes, acitretin, tacrolim-us, cytokines

Abstract

Psoriasis is a skin infection disease that is related to dysfunction of the immune system. Plaque psoriasis is a common and typical psoriasis; it can be triggered by multiple factors, for example, environmental triggers and genetic factors. Skin with plaque psoriasis can be itchy and red, appear inflamed, and have scaly patches; the infected region can last for months and may leave permanent pigmentation. Keratinocytes (skin cells) are related to psoriasis; as homeostasis is disturbed, excess keratinocytes are produced, and surplus skin cells lead to psoriasis. Acitretin and tacrolimus are both drugs that can help with psoriasis but with different mechanisms.

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Published

2025-07-06