Advances in Oral Squamous Cell Carcinoma: Pathogenesis, Risk Factors

Abstract

mwymwAbstract: Among many types of Oral Cancer, Oral Squamous cell carcinoma(OSCC) is one of the most significant malignant tumors in the world. When more research is done into the molecular pathogenesis behind tumor initiation and progression, there is an opportunity to discover targeted therapies that are more effective for treatment. Moreover, in the study of tumor microenvironment,the interaction among cancer cells and surrounding stroma or immune cells, is also still not well understood. Understanding the interactions between molecules in the tumor microenvironment has important implications for the study of new therapeutic targets. The symptoms, pathogenesis and risk factor of OSCC as well as the existing therapeutic methods were studied in this paper. Because there are no obvious symptoms in the early stages of OSCC, it is important to know it for the treatment of OSCC. Risk factor also discussed the main causes of OSCC, which also can be contributed to the subsequent research. In this paper, common and popular therapies are listed. nanotechnology-based drug delivery is one of the most novel and effective therapies available today. This method offers the possibility of delivering chemotherapy or targeted drugs directly to OSCC. This reduces systemic side effects and provides precision. This technology has shown amazing effects in the clinical scope and is gradually being used in treatment.