Risk Factors, Prevention and Intervention Strategy of Parkinson Disease
DOI:
https://doi.org/10.61173/06zjjs49Keywords:
Parkinson Disease, Risk factors, Prevention, InterventionAbstract
Parkinson disease (PD) is a kind of popular neurodegenerative disease which mainly affects old people. It has already become one of the most popular nervous disease around the globe, second only to Alzheimer disease. And the topic of PD is attracting increasingly widespread social attention in recent years. Hence, this article aims to collect and conclude basic information about risk factors, prevention and intervention of PD by searching relative essays, as well as giving some strategy to fight against PD. First, this article states such risk factors that trigger PD and analyses the pathogenesis. Secondly, the ways to prevent PD and how to screen PD patients are introduced. Finally, the article writes about nowadays how do people interfere the PD, including two methods which are medicines and operation. Also, this part gives some disadvantages and limitation of each method. Finally, there is some vision of the future and suggestions about future researching direction of PD.
References
[1] New Estimate Suggests 25 Million People with Parkinson’s by 2050. https://www.michaeljfox.org/news/new-estimatesuggests-25-million-people-parkinsons-2050
[2] He Lei, Bai Lingxia, An Hongyan, et al. Efficacy of Selegiline Combined with Amantadine Tablets in the Treatment of Parkinson’s Disease and Its Influence on the Nrf2/HO-1 Protein Pathway [J]. Journal of Brain and Nervous Diseases, 2025, 33(08): 516 - 521.
[3] Jing Yun, Gao Xiyan, Wang Linlin, et al. Randomized Controlled Trial on the Clinical Efficacy and Safety of Acupuncture Combined with Levodopa in the Treatment of Parkinson’s Disease [J]. Journal of Traditional Chinese Medicine, 2025, 66(14): 1456 - 1462.
[4] Shao Lingyun, Liu Biaohu. Research Progress on the Interaction between the Genetic Mechanisms and Related Risk Factors of Parkinson’s Disease [J]. Geriatrics & Health Care, 2025, 31(02): 592 - 596.
[5] Zhou Yuguang, Su Ying, Liu Yaling, et al. Accelerated Establishment of a Parkinson’s Disease Model Based on Injection of α - Synuclein Fibrils in A53T Transgenic Mice [J/ OL]. Acta Laboratorium Animalis Scientia Sinica, 1 - 8 [2025 - 09 - 06].
[6] Liu Haoyu. Exploration of the Global Epidemiological Dean&Francis Haoming Yi Trends of Parkinson’s Disease and the Role of Related Environmental Factors Based on GBD Data [D]. Bengbu Medical College, 2024.
[7] Zhang Ping. Prevention and Treatment Strategies for Parkinson’s Disease Induced by Environmental Toxins. Jiangxi Province, Jiangxi Provincial People’s Hospital, 2022 - 03 - 28.
[8] Raj K, Kaur P, Gupta GD, Singh S. Metals associated neurodegeneration in Parkinson’s disease: Insight to physiological, pathological mechanisms and management. Neurosci Lett. 2021 May 14;753:135873.
[9] Zhou Rong, He Jiao, Lu Hong. Research Progress on the Role of Metal Ions in the Pathogenesis of Parkinson’s Disease [J]. Chinese Journal of Neurology, 2019, 52(6): 516 - 520.
[10] Hindle JV. Ageing, neurodegeneration and Parkinson’s disease. Age Ageing. 2010 Mar;39(2):156 - 61.
[11] Coleman C, Martin I. Unraveling Parkinson’s Disease Neurodegeneration: Does Aging Hold the Clues? J Parkinsons Dis. 2022;12(8):2321 - 2338.
[12] Wang Yajie, Liu Weiguo, Yu Cuiyu, et al. Characteristics of Non - motor Symptoms and Gender Differences in Newly Diagnosed Patients with Parkinson’s Disease [J]. Journal of Apoplexy and Nervous Diseases, 2022, 39(01): 28 - 32.
[13] Qiao Zimei, She Meilin. How to Prevent Parkinson’s Disease in the Early Stage [J]. Health Must - Read, 2025, (13): 50 - 52.
[14] Liu Xia. Dogs Can Accurately Identify Parkinson’s Patients [N]. Science and Technology Daily, 2025 - 08 - 01(004).
[15] “AI Magic Brush” Can Identify Parkinson’s Disease [J]. New Life of Science, 2025, 28(07): 6.
[16] Deep brain stimulation. https://www.mayoclinic.org/testsprocedures/deep-brain-stimulation/care-at-mayo-clinic/pcc- 20384564
[17] Zhang Doudou, Cai Xiaodong. Research on an Automatic Target Localization Method for STN - DBS Surgery in Parkinson’s Disease Based on the U - Net Network [C]// Chinese Medical Doctor Association, Neurosurgical Physician Branch of Chinese Medical Doctor Association. Abstracts of the 18th Annual Meeting of Neurosurgical Physicians of Chinese Medical Doctor Association - Functional Neurosurgery. The First Affiliated Hospital of Shenzhen University (Shenzhen Second People’s Hospital);, 2024: 206 - 207.
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