How Technological Innovation Reshapes the Paradigm of Disease Prediction and Treatment
DOI:
https://doi.org/10.61173/w66hqz83Keywords:
Paradigm shift, Precision medicine, Artificial intelligence, Digital technologyAbstract
This paper adopts a macro perspective spanning the philosophy of technology and the history of medicine to systematically argue that the technological innovation cluster—comprising big data, artificial intelligence, and biotechnology—has disrupted the traditional medical paradigm. We first deconstruct the old paradigm characterized by “reactive diagnosis and treatment, standardized protocols, and physician-centered care” along with its inherent limitations. We then delve into the synergistic disruptive mechanisms generated by the technology cluster through three dimensions: “data-driven cognition,” “intelligent algorithms reshaping decisionmaking,” and “biotechnology redefining interventions.” This reveals three defining features of the new paradigm: At the practice level, it enables precision prediction and dynamic intervention based on individualized data; At the agency level, it establishes a collaborative relationship among physicians, AI, and patients. The study also highlights the new paradigm’s ethical challenges, including data privacy and algorithmic fairness, providing crucial insights for understanding contemporary medical transformation and planning future healthcare systems.
References
[1] Elwyn, G., Frosch, D., Thomson, R., Joseph-Williams, N., Lloyd, A., Kinnersley, P., ... & Barry, M. (2012). Shared decision making: a model for clinical practice. Journal of general internal medicine, 27(10), 1361-1367.
[2] Bodenheimer, T., Chen, E., & Bennett, H. D. (2009). Confronting the growing burden of chronic disease: can the US health care workforce do the job?. Health affairs, 28(1), 64-74.
[3] Ali, S., Qadri, Y. A., Ahmad, K., Lin, Z., Leung, M. F., Kim, S. W., ... & Zhou, T. (2025). Large Language Models in Genomics— A Perspective on Personalized Medicine. Bioengineering, 12(5), 440.
[4] Evans, W. E., & Relling, M. V. (2004). Moving towards individualized medicine with pharmacogenomics. Nature, 429(6990), 464-468.
[5] Hood, L., Brogaard, K. R., Price, N. D., & Flores, M. A. (2013). Systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory. In Handbook of Systems Biology (pp. 445-467).
[6] Jameson, J. L., & Longo, D. L. (2015). Precision medicine— personalized, problematic, and promising. Obstetrical & gynecological survey, 70(10), 612-614.
[7] Schork, N. J. (2015). Personalized medicine: time for oneperson trials. Nature, 520(7549), 609-611.
[8] Steinhubl, S. R., Muse, E. D., & Topol, E. J. (2015). The emerging field of mobile health. Science translational medicine, 7(283), 283rv3-283rv3.
[9] Istepanian, R. S. (2022). Mobile health (m-Health) in retrospect: the known unknowns. International journal of environmental research and public health, 19(7), 3747.
[10] Sweileh, W. M., Al-Jabi, S. W., AbuTaha, A. S., Zyoud, S. E. H., Anayah, F. M., & Sawalha, A. F. (2017). Bibliometric analysis of worldwide scientific literature in mobile-health: 2006–2016. BMC medical informatics and decision making, 17(1), 72.
[11] Topol, E. (2019). Deep medicine: how artificial intelligence can make healthcare human again. Hachette UK.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 by the authors.

This work is licensed under a Creative Commons Attribution 4.0 International License.
