The Relationship Between Alcohol Consumption and Liver Status, For US People in Age 18-64, Contr ol Sex and Modified by BMI And Age

Abstract

Alcohol consumption and liver function have become increasingly important issues in modern society. Numerous studies have investigated their relationship; this study focuses on U.S. adults from 2017 to 2020 to examine the association between alcohol consumption and liver function, assessed by alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT), while controlling for sex and evaluating modification by body mass index (BMI) and age. Linear regression models were applied to estimate associations. The results indicate that alcohol consumption is strongly associated with liver enzyme levels, and this relationship is confounded by sex and modified by BMI. These findings emphasize the importance of considering demographic and metabolic factors when evaluating alcohol-related liver injury and provide new evidence for targeted prevention and intervention strategies in public health. Future research should adopt longitudinal designs to clarify causal pathways and quantify the potential benefits of integrated prevention strategies.