Effects of High-Fiber Diets on Type 2 Diabetes Mellitus in China
DOI:
https://doi.org/10.61173/xmcvtc56Keywords:
High-Fiber Diet, type 2 diabetes, metabolic disordersAbstract
Amid continued socioeconomic development and improvements in living conditions in China, the population affected by type 2 diabetes mellitus has steadily expanded, thereby imposing a substantial and growing burden on the public health system and the broader economy. At present, lifestyle-based adjunctive interventions for patients with type 2 diabetes mellitus have yielded encouraging results; among these, high-fiber dietary patterns—capable of markedly enhancing intestinal microbiota diversity and improving metabolic profiles—have attracted widespread attention. Drawing on a randomized controlled trial of a high-fiber dietary intervention in 43 adults with type 2 diabetes mellitus, together with corroborating observational data from large population cohorts, the literature outlines a coherent evidence chain indicating that high-fiber dietary interventions can effectively improve clinical metabolic outcomes in this patient population. This review synthesizes and evaluates the modulatory effects of highfiber diets on the gut microbiota and its metabolites among Chinese patients with type 2 diabetes mellitus, and— based on identified mechanistic and observational evidence as well as their limitations—proposes practice-oriented design recommendations and priority areas for future comprehensive management.
References
[1] International Diabetes Federation. IDF Diabetes Atlas, 11th ed. 2025.
[2] Qin J, et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature, 2012, 490(7418): 55-60.
[3] Reynolds A, et al. Dietary fibre and glycemic control: a systematic review and meta-analysis. Lancet, 2019, 393(10170): 434-445.
[4] Cui S, et al. Association of intestinal microbiota markers with dietary patterns in Chinese patients with T2DM. Frontiers in Public Health, 2022, 10(2): 9709334.
[5] Fu J, et al. Habitual dietary fiber intake, gut microbiota and HbA1c in Chinese type 2 diabetes patients. Nutrients, 2022, 14(5): 1003.
[6] Zhao L, et al. Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes. Science, 2018, 359(6380): 1151- 1156.
[7] Guo H, et al. Effects of soluble fiber supplementation on glycemic control in T2DM: a meta-analysis. Clinical Nutrition, 2020, 39(7): 2265-2273.
[8] Młynarska E, et al. Gut microbiota in diabetes pathogenesis and management. Nutrients, 2024, 16(12): 19-38.
[9] Tolhurst G, et al. Short-chain fatty acids stimulate GLP-1 secretion via FFAR2. Diabetes, 2012, 61(2): 364-371.
[10] Chen J, et al. Dietary fiber intake, gut microbiota and risk of type 2 diabetes: a prospective study. Circulation Research, 2024, 134(4): 538-553.
[11] Christensen L, et al. Microbial enterotypes in personalized nutrition and obesity management. American Journal of Clinical Nutrition, 2018, 108(4): 645-651.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 by the authors.

This work is licensed under a Creative Commons Attribution 4.0 International License.
