Assessment of the Pr os and Cons of Bioactive Glass Composites in the Repair of Dental Hard Tissues

Authors

  • Xinwo Li

DOI:

https://doi.org/10.61173/p9ck6r94

Keywords:

Bioactive glass, dental hard tissue, remineralization, antibacterial, composites

Abstract

Bioactive glass (BAG), a bioactive material with excellent biocompatibility, has been increasingly utilized in the field of dental restoration. Along with the changes in clinical demands and the upgrading of preparation processes, the common types of BAG currently include nanobioactive glass, mesoporous bioactive glass, and bioactive glass composites, which show significant differences in mechanical strength, binding stability, preparation cost and bioactivity. This article compares the differences in physical properties, preparation methods, and functional activities among various bioactive glasses. We highlight the superior mechanical strength, drug-loading capacity, broad-spectrum antibacterial efficacy, and pronounced tissue-regenerative capacity of each BAG variant across multiple dimensions. The results indicate that bioactive glass composites have obvious advantages in mechanical properties, degradation rate regulation, and remineralization promotion compared with other BAG materials. These findings aim to provide guidance for material selection in dental hard tissue remineralization and systematically summarize the functional similarities and differences among various BAGs, offering new ideas for the future development of bioactive glass composites with broader adaptability.

References

[1] Attik N, Gauthier R, Ahmed M. Bioactive Glass-Based Materials for Soft and Hard Tissue Regeneration: A New Future for Dental and Biomedical Applications. Materials (Basel). 2023 Sep 15;16(18):6238.

[2] Simila HO, Boccaccini AR. Sol-gel bioactive glass containing biomaterials for restorative dentistry: A review. Dent Mater. 2022 May;38(5):725-747.

[3] Tabassum S, Saqib M, Batool M, et al. Eco-friendly synthesis of mesoporous bioactive glass ceramics and functionalization for drug delivery and hard tissue engineering applications. Biomed Mater. 2024 Mar 12;19(3).

[4] Mazurek Ł, Szudzik M, Rybka M, et al. Silk Fibroin Biomaterials and Their Beneficial Role in Skin Wound Healing. Biomolecules. 2022 Dec 12;12(12):1852.

[5] Choe YE, Kim YJ, Jeon SJ, et al. Investigating the mechanophysical and biological characteristics of therapeutic dental cement incorporating copper doped bioglass nanoparticles. Dent Mater. 2022 Feb;38(2):363-375.

[6] Kaou MH, Furkó M, Balázsi K, et al. Advanced Bioactive Glasses: The Newest Achievements and Breakthroughs in the Area. Nanomaterials (Basel). 2023 Aug 9;13(16):2287.

[7] Fallahzadeh F, Heidari S, Najafi F, et al. Efficacy of a Novel Bioactive Glass-Polymer Composite for Enamel Remineralization following Erosive Challenge. Int J Dent. 2022 Apr 22;2022:6539671.

[8] Geng Vivanco R, Tonani-Torrieri R, Souza ABS, et al. Effect of natural primer associated to bioactive glass-ceramic on adhesive/dentin interface. J Dent. 2021 Mar;106:103585.

[9] Meskher H, Sharifianjazi F, Tavamaishvili K, et al. Limitations, challenges and prospective solutions for bioactive glasses-based nanocomposites for dental applications: A critical review. J Dent. 2024 Nov;150:105331.

[10] Wang W, Chen R, Xie Y, et al. Research progress of bioactive glass in the remineralization of dental hard tissue. Biomed Phys Eng Express. 2025 Aug 28;11(5).

Downloads

Published

2026-02-28