Down-regulating CD4+CD25+T Cells Could Benefit CHB Patient with Mildly Elevated Alanine Aminotransferase by Applying Chinese Traditional Medicine

Abstract

The hepatitis B virus (HBV) causes hepatitis B, an acute liver illness that raises the risk of liver failure, liver cancer, and cirrhosis. Chronic refers to a condition that lasts longer than six months. Currently, treatment is more biased toward severe patients. However, the therapy for patients with elevated ALT is also necessary but needs to be addressed. This paper will explore how the Chinese Traditional Medicine Bushen formula could benefit CHB patients will elevate ALT by reducing the number of CD4+CD25+T Cells. This work will use Flourescence-Activated Cell Sorter (FACS) and real-time PCR to measure the percentage of T-reg cells in mice with elevated ALT levels after treatment with the Bushen formula. The effectiveness of the Bushen formula on CHB patients has been proved in this paper, which could help millions of patients to have a better life quality once the side effects and the dosage for each individual are explored further.