Progress in Improving Metabolic Syndrome with Adzuki Bean

Abstract

Metabolic syndrome (MS) is a clinical condition characterized by the simultaneous onset of abdominal obesity, abnormal blood sugar levels, dyslipidemia, and hypertension. It significantly impacts overall health and exhibits an increasing prevalence with a decreasing age of onset. Metabolic syndrome affects approximately one quarter of the global population, posing a critical threat to human well-being as a major public health concern. Current approaches for prevention and management primarily rely on pharmaceutical interventions or lifestyle modifications; however, their effectiveness remains limited. In recent years, the concept of food-medicine homology has emerged as a novel theory that holds promise in alleviating metabolic syndrome. Adzuki bean, a widely cultivated legume rich in various nutrients and bioactive compounds, has been traditionally recognized in Chinese medicine for its beneficial effects on invigorating QI (vital energy), arming the middle (digestive system), strengthening the spleen (immune function), and eliminating dampness (excess moisture). Numerous studies have demonstrated that adzuki bean can effectively regulate blood sugar levels, lipid profiles, blood pressure while improving gut microbiota imbalances and exhibiting anti-obesity properties to some extent. As such, it can serve as an adjunct therapy for managing metabolic syndrome. Compared to conventional drugs used for this purpose, adzuki bean offers safer alternatives with diverse product options. These findings provide valuable theoretical foundations and practical references for preventing and treating diseases associated with metabolic syndrome.